Remembering MARCH 16, 2011 KOSEN-RUFU DAY

Wishing you all a promising and fruitful Kosen Rufu Day, 16 March 2013.

Sensei - President Daisaku Ikeda is amazingly active - truly a person born to encourage and inspire people around the world

====[ Let's flap our wings together ]====

Let's flap our wings together, like the migratory birds - travel far and wide across continent and achieving their aims with ease and benefits to all. We as human can achieve the much needed peace and prosperity together....

[Thinking Aloud]

The power and benefits of being together or as a team is much evident with example from nature itself - as we observed migratory birds flying very very long distances across continents with much ease... unlike or almost impossible feat achieved... if ventured all alone.

From what I heard/read - these migratory birds flew with certain techniques - flapping their wings together, formation, angle of flight etc - the physics involved, thus enabling them to achieve the impossible.
Likewise, if, we as human could work/contribute together CAN achieve the impossible with much ease and benefit one and all.

The topic itself was reminded to me by one of my esteemed friend.. also here in Facebook @Erendro Leichombam while we were having a discussion at his residence some time back.

My earnest wish and prayer for all is to come together and work for a common cause on issues affecting us. It will definitely be beneficial to one and all - in equal terms and we all can live happily ever and after.
I have a strong believe - that this is possible in our current society - with a little bit of help from each other - to PRACTICE equally - we all can achieve wonders and esp those issues with urgent need for intervention - for all human to be happy and healthy together towards a prosperous society here in Manipur. {NMRK}

Correct me please or suggest - 

We got to do - what we got to do !!!

Researchers make heroin addiction breakthrough

Scientists have made an important step in helping people who are suffering from addiction to opioid drugs like heroin.

A team from Adelaide and Colorado universities has discovered a receptor in the body's immune system that increases addiction to drugs such as heroin and morphine.

Both the central nervous and the immune systems influence addiction, but the study has shown only the immune response in the brain needs to be blocked to prevent cravings for opioid drugs.

They have found that the immune-addiction response can be blocked by a drug known as plus-naloxone.

The study's lead author, University of Adelaide research fellow Mark Hutchinson, says the results could eventually lead to new drugs that help patients with severe pain, as well as helping heroin users kick the habit.

"We're really excited about the opportunities that this presents for us in understanding the basic science behind drug addiction but also from the clinical perspective, the opportunities that it presents for safer pain relief and potentially treatment of drug addiction," he said.

Dr Hutchinson says opioid addiction is created when the chemical dopamine is produced in the brain, which causes a sense of 'reward' in the user.

He says plux-naxolone prevents that reaction from occurring.

"It really changes what we understand is actually happening in the brain and based on what we understand is happening in the brain," he said.

"We'd previously thought that the addiction was created by the wiring of the brain and solely the wiring of the brain.

"But what our study shows is that the immune-receptor Toll-Like receptor 4 is crucial for drug-reward to opioids and our drug specifically blocks this and nullifies the rewarding properties of opioids."

Dr Hutchinson says the discovery has implications ranging far beyond treating drug addiction.

"This is not just about drug addicts, it's for those.. anybody who's taking opioid pain medications that might become addicted to these problematic drugs, so really these discoveries have opportunities to impact a wide variety of everyday people," he said.

'Absolute breakthrough'
The federal president of the Australian Medical Association, Dr Steve Hambleton, says the work changes what scientists understand about opioids and addiction.

"This is an absolute breakthrough in this area and I was really excited to read this material, and particularly interested because here it is, again Australia, University of Adelaide, coming up with a really world-breaking opportunity," he said.

Dr Hambleton says the study has the potential to lead to major advances in patient and palliative care.

"Who could benefit? Nearly everyone in the population is going to need pain management at some time in their life and so this could be very widely applicable," he said.

"That if we could block that addiction potential for multiple different molecules by having a look at this particular immune system molecule, that's going to have very broad implications."

He says the research could lead to drugs that help with chronic pain without the risk of becoming addictive.

"We do have trouble managing chronic pain, we do have trouble with diversion of pain medicine into illicit markets and it looks like there's now been clarification of exactly how this addiction process works and it doesn't stop the ability for us to stop pain," he said.

"[It will be] very, very good for clinical use, if we can get it to market."

Clinical trials are expected in the next two years.

Topics: drug-use, medical-research, addictive, health, australia, sa, adelaide-5000

First posted Wed Aug 15, 2012 8:04am AEST

(Courtesy : http://www.abc.net.au/news/2012-08-15/researchers-make-heroin-addiction-breakthrough/4199096)
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